Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295848 | 1.00 | CTSK (0.48) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL7376384 | 1.00 | CTSK (0.48) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL9741659 | 1.00 | CTSK (0.48) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL7381049 | 0.89 | CTSK (0.51) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL8021226 | 0.89 | CTSK (0.51) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL10270880 | 0.85 | CTSK (0.46) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL9104071 | 0.85 | CTSK (0.55) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL9104062 | 0.85 | CTSK (0.55) | CTSKCTSSCTSLCTSBAAK1 | |
| SCHEMBL19337882 | 0.85 | CTSK (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30154195 | 0.85 | CTSK (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122610-A | Renin inhibitor intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-16 | — | — | US | disclosed |