Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741587 | 0.85 | MAOB (0.41) | CASRMAPTHSD17B10POLBALDH1A1 | |
| SCHEMBL7445525 | 0.85 | POLB (0.57) | KDM4EGAACASRMAPTHSD17B10 | |
| SCHEMBL9395591 | 0.80 | GRIA1 (0.53) | KDM4EGAAMAPTHSD17B10TP53 | |
| SCHEMBL9364677 | 0.79 | KDM4E (0.46) | KDM4EGAAMAPTHSD17B10TP53 | |
| SCHEMBL31236070 | 0.74 | POLB (0.69) | KDM4EHSD17B10POLBALDH1A1HPGD | |
| SCHEMBL7282502 | 0.74 | POLB (0.69) | KDM4EHSD17B10POLBALDH1A1HPGD | |
| SCHEMBL30930127 | 0.73 | MAOB (0.64) | KDM4EMAPTHSD17B10POLBALDH1A1 | |
| SCHEMBL7367213 | 0.73 | MAOB (0.64) | KDM4EMAPTHSD17B10POLBALDH1A1 | |
| SCHEMBL22292503 | 0.72 | GRIA1 (0.63) | KDM4EMAPTHSD17B10ALDH1A1THRB | |
| SCHEMBL9395728 | 0.71 | GRIA1 (0.53) | KDM4EGAAMAPTHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004350-A1 | OXYGENATED QUINOXALINES | THE UPJOHN COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |