Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21123 | 0.86 | ALDH1A1 (0.37) | TSHRALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL9618988 | 0.85 | ALDH1A1 (0.44) | TSHRMAPK1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL246085 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| Potassium SCHEMBL3422897 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| Calcium SCHEMBL4817089 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL3063255 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| Water SCHEMBL3409395 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL20564124 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL20565064 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL41996 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132323-A | Treatment of animals | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-07-21 | — | — | US | disclosed |