Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742123 | 1.00 | CNR2 (0.41) | CNR2TTRTDP1LCKMEN1 | |
| SCHEMBL1822108 | 0.83 | TTR (0.52) | TTRTDP1LCKMEN1KMT2A | |
| SCHEMBL1822107 | 0.83 | TTR (0.52) | TTRTDP1LCKMEN1KMT2A | |
| SCHEMBL2639146 | 0.81 | ERN1 (0.53) | TTRMEN1KMT2ACYP3A4HPGD | |
| SCHEMBL20439457 | 0.77 | CYP3A4 (0.44) | CNR2LCKMEN1KMT2ACYP3A4 | |
| SCHEMBL28148942 | 0.77 | ERN1 (0.41) | CNR2TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL9742937 | 0.74 | TTR (0.50) | CNR2TTRTDP1CYP3A4HPGD | |
| SCHEMBL9742941 | 0.74 | TTR (0.50) | CNR2TTRTDP1CYP3A4HPGD | |
| SCHEMBL1010817 | 0.73 | CNR2 (0.38) | CNR2CYP3A4TYRALOX5 | |
| SCHEMBL9744278 | 0.73 | CYP3A4 (0.39) | TTRTDP1LCKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |