SCHEMBL1822108

SCHEMBL1822108

Oc1cc(O)c(C=Cc2c(O)cc(O)cc2O)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 4/20 0.52
▸ LCK P06239 2/20 0.45
▸ BACE1 P56817 1/20 0.44
▸ NQO1 P15559 1/20 0.41
▸ ALOX5 P09917 3/20 0.39
▸ PTPN1 P18031 2/20 0.39
▸ MMP2 P08253 2/20 0.39
▸ CYP1A1 P04798 2/20 0.39
▸ TYR P14679 2/20 0.39
▸ PTGS1 P23219 2/20 0.39
▸ CYP1B1 Q16678 2/20 0.39
▸ SYNJ2 O15056 1/20 0.39
▸ BCHE P06276 1/20 0.39
▸ PTPN22 Q9Y2R2 1/20 0.39
▸ TDP1 Q9NUW8 3/20 0.39
▸ MEN1 O00255 5/20 0.38
▸ CYP3A4 P08684 5/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ HPGD P15428 4/20 0.38
▸ MAPT P10636 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1822107 1.00 TTR (0.52) TTRLCKBACE1NQO1ALOX5
SCHEMBL9742118 0.83 CNR2 (0.41) TTRLCKBACE1NQO1ALOX5
SCHEMBL9742123 0.83 CNR2 (0.41) TTRLCKBACE1NQO1ALOX5
SCHEMBL1824473 0.81 TTR (0.68) TTRBACE1ALOX5PTPN1MMP2
SCHEMBL9744884 0.81 TTR (0.59) TTRLCKALOX5PTPN1PTGS1
SCHEMBL9744878 0.81 TTR (0.59) TTRLCKALOX5PTPN1PTGS1
SCHEMBL1824476 0.81 TTR (0.68) TTRBACE1ALOX5PTPN1MMP2
SCHEMBL30436839 0.79 LCK (0.71) TTRLCKBACE1ALOX5PTPN1
SCHEMBL1818961 0.79 LCK (0.71) TTRLCKBACE1ALOX5PTPN1
SCHEMBL1818963 0.79 LCK (0.71) TTRLCKBACE1ALOX5PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 — — EP claimed
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 — — EP claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 — — WO claimed
EP-3654929-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2020-05-27 — — EP claimed
WO-2019016153-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2019-01-24 — — WO claimed
EP-2315583-B1 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2018-05-09 — — EP claimed
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE PECHERE LAURENT 2011-07-28 — — US claimed
EP-2005941-A2 Cellular rejuvenation compounds Henkel AG & Co. KGaA (DE) 2008-12-24 — — EP claimed
EP-1068864-B1 Use of at least one hydroxystilbene as glycation inhibitor OREAL (FR) 2005-02-09 — — EP claimed
EP-1064931-B1 Cosmetic composition containing at least one hydroxystilbene and ascorbic acid OREAL (FR) 2004-12-15 — — EP claimed
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene L'OREAL (FR) 2002-12-05 — — US claimed
EP-1234571-A1 Topical composition containing a hydroxystilbene and a polyol L'OREAL (FR) 2002-08-28 — — EP claimed
US-6440433-B1 TREATING MENOPAUSAL SKIN DISORDERS; APPLYING TOPICAL MIXTURE TO IMPART AGING RESISTANCE; ACTIVATING SKIN FIBROBLAST PROLIFERATION SOCIETE L'OREAL S.A. (FR) 2002-08-27 — — US claimed
EP-1068864-A1 Use of at least a hydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-01-17 — — EP claimed
EP-1064931-A1 Cosmetic composition containing at least an hydroxystilbene and ascorbic acid L'OREAL (FR) 2001-01-03 — — EP claimed
US-6147121-A TOPICALLY APPLYING HYDROXYSTILBENE DERIVATIVE TO TREAT SKIN AGING AND WRINKLES SOCIETE L'OREAL S.A. (FR) 2000-11-14 — — US claimed
US-6124364-A Desquamation/epidermal renewal of the skin and/or combating skin aging SOCIETE L'OREAL S.A. (FR) 2000-09-26 — — US claimed
EP-0953346-A1 Use of at least a hydroxystilbebe in a skin fortifying composition L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953345-A1 Use of at least a hydroxystilbene as an agent for decreasing micro-organism adhesion L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953344-A1 Use of at least one hydroxystilbene in a composition to stimulate desquamation of the skin and compositions containing it L'OREAL (FR) 1999-11-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE FABP2, SI, SLC10A2 TTR 523/4885LCK 3753/4885BACE1 1722/4885
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene CYP8B1, HSD17B1, HSD11B1 TTR 3195/4885LCK 3170/4885BACE1 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback