Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744780 | 0.80 | BLM (0.38) | KMT2AALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL19350092 | 0.80 | SMN1; SMN2 (0.35) | KMT2AALDH1A1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL9742694 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1CCR8 | |
| SCHEMBL1207583 | 0.73 | CCR8 (0.35) | KMT2AALDH1A1CCR8KDM4E | |
| SCHEMBL14113784 | 0.71 | KMT2A (0.36) | KMT2AALDH1A1EGLN1 | |
| SCHEMBL19349237 | 0.71 | — | — | |
| SCHEMBL14113838 | 0.70 | ATM (0.31) | — | |
| SCHEMBL14113785 | 0.67 | HPGD (0.38) | KMT2AALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL31023340 | 0.67 | CCR8 (0.44) | KMT2AALDH1A1RAB9AADORA2AADORA1 | |
| SCHEMBL14113840 | 0.67 | HSD17B10 (0.35) | KMT2AALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |