Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742201 | 0.80 | KMT2A (0.33) | KDM4EALDH1A1POLBRAB9AKMT2A | |
| SCHEMBL1207583 | 0.79 | CCR8 (0.35) | KDM4EALDH1A1MAPTKMT2ACCR8 | |
| SCHEMBL30094853 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL9742694 | 0.76 | KMT2A (0.41) | ALDH1A1KMT2ACCR8 | |
| SCHEMBL14113784 | 0.76 | KMT2A (0.36) | ALDH1A1KMT2A | |
| SCHEMBL26091349 | 0.75 | ALDH1A1 (0.41) | BLMGFERMPOCYP3A4KDM5A | |
| SCHEMBL25367893 | 0.73 | MAPT (0.39) | BLMGFERMPOCYP3A4KDM5A | |
| SCHEMBL21190834 | 0.73 | RAB9A (0.41) | BLMGFERMPOCYP3A4KDM5A | |
| SCHEMBL14113785 | 0.72 | HPGD (0.38) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL29042806 | 0.72 | RAB9A (0.41) | BLMGFERMPOCYP3A4KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | claimed |