Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335808 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL8184 | 0.90 | — | — | |
| Water SCHEMBL28946191 | 0.90 | — | — | |
| Bromide SCHEMBL11873102 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL27788135 | 0.88 | LMNA (0.59) | LMNAMAPTTSHRCYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL811011 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL28102339 | 0.88 | LMNA (0.59) | LMNAMAPTTSHRCYP1A2HSD17B10 | |
| SCHEMBL377126 | 0.87 | — | — | |
| SCHEMBL29642937 | 0.84 | LMNA (0.53) | LMNAMAPTTSHRCYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL1953067 | 0.84 | LMNA (0.62) | LMNAMAPTTSHRCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114855-A | Method for aggregating cells with small microspheres | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0192705-A1 | DETACHMENT OF ANCHORAGE-DEPENDENT CELLS FROM MICROCARRIERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1986-09-03 | — | — | EP | disclosed |
| WO-1986001531-A1 | DETACHMENT OF ANCHORAGE-DEPENDENT CELLS FROM MICROCARRIERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1986-03-13 | — | — | WO | disclosed |