Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742227 | 1.00 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8808623 | 1.00 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8810053 | 0.88 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9740243 | 0.88 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9740249 | 0.88 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9741121 | 0.86 | ABCC9 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8808513 | 0.86 | ABCC9 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9741115 | 0.86 | ABCC9 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8810350 | 0.85 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9740724 | 0.85 | ABCB1 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |