Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL4877303 | 0.84 | — | — | |
| Propionitrile SCHEMBL14798238 | 0.79 | — | — | |
| SCHEMBL124304 | 0.78 | — | — | |
| SCHEMBL22272369 | 0.78 | — | — | |
| Butane SCHEMBL9542950 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL16037462 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL56391 | 0.76 | — | — | |
| Acetonitrile SCHEMBL19611744 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHR | |
| SCHEMBL7564122 | 0.74 | — | — | |
| Dimethyl Sulfoxide SCHEMBL15093043 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084716-A | IMAGE FORMING APPARATUS USING ELECTRIC CURRENT TO TRANSFER INK TO A MASTER AND REMOVE EXCESS INK FROM THE MASTER BEFORE TRANSFERRING THE REMAINING INK TO RECORDING MEDIUM | CANON KABUSHIKI KAISHA (JP) | 1992-01-28 | — | — | US | disclosed |