Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181774 | 0.81 | CYP1A2 (0.55) | PTPN1ALDH1A1ALOX15AKR1C3TYMS | |
| SCHEMBL27861812 | 0.79 | SMN1; SMN2 (0.49) | FOLH1ALDH1A1ALOX15KDM4EHSD17B10 | |
| SCHEMBL29118850 | 0.77 | HNF4A (0.47) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL4802119 | 0.74 | HNF4A (0.49) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL17164118 | 0.74 | NR4A1 (0.52) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL31517118 | 0.73 | HNF4A (0.61) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL1479704 | 0.73 | HNF4A (0.61) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL12006684 | 0.72 | HNF4A (0.55) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL607218 | 0.72 | HNF4A (0.50) | HNF4AFOLH1PTPN1FABP3FABP4 | |
| SCHEMBL6537038 | 0.72 | HNF4A (0.71) | HNF4AFOLH1PTPN1FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138010-A | Fast switching polysiloxane ferroelectric liquid crystals | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-11 | — | — | US | disclosed |