Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HK2 | P52789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743209 | 1.00 | ESR2 (0.35) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL9744332 | 0.82 | IAPP (0.50) | KDM4EALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL9744335 | 0.82 | IAPP (0.50) | KDM4EALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL5431853 | 0.78 | GABRA1 (0.50) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL28497673 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1MEN1POLBMAPT | |
| SCHEMBL9313934 | 0.74 | ESR2 (0.37) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL9806449 | 0.74 | SELL (0.37) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL978929 | 0.74 | GABRA1 (0.55) | KDM4EALDH1A1MEN1LMNAPOLB | |
| SCHEMBL9742172 | 0.73 | EGFR (0.43) | ALDH1A1PTGS2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL9744034 | 0.73 | TYR (0.54) | CYP3A4MEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |