SCHEMBL9743282

SCHEMBL9743282

O=C(Oc1ccc(O)c(O)c1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.66
MAPT P10636 4/20 0.66
MEN1 O00255 3/20 0.66
TDP1 Q9NUW8 2/20 0.66
PARP10 Q53GL7 1/20 0.56
NSD2 O96028 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 1/20 0.53
PKM P14618 1/20 0.53
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
POLB P06746 1/20 0.53
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
RAB9A P51151 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624925 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL27725555 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL7030719 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL7711402 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL14859395 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL2298714 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL12732134 0.84 LMNA (0.62) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL28462785 0.84 KMT2A (0.60) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL9299759 0.83 NSD2 (0.73) KMT2AMAPTMEN1TDP1PARP10
SCHEMBL563931 0.83 HPGD (0.69) KMT2AMAPTMEN1TDP1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108239191-A A kind of alkoxyl magnesium carrier model catalyst component for olefin polymerization, catalyst and its application 北京利和知信科技有限公司 2018-07-03 CN disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed