Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162057 | 0.87 | ESR1 (0.73) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL9743098 | 0.86 | ESR1 (0.66) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL16039283 | 0.83 | KMT2A (0.51) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL27852004 | 0.83 | ESR1 (0.67) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL5179548 | 0.83 | ESR1 (1.00) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL28665120 | 0.83 | KMT2A (0.51) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL10534799 | 0.81 | ESR1 (0.65) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL1918507 | 0.81 | KMT2A (0.71) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL27893218 | 0.80 | TSHR (0.59) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL17430808 | 0.80 | KMT2A (0.60) | ESR1ESR2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |