Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851941 | 0.87 | ESR1 (0.62) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5162057 | 0.84 | ESR1 (0.73) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27939856 | 0.83 | ESR1 (0.55) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9743288 | 0.83 | ESR1 (0.71) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2060065 | 0.82 | KMT2A (0.49) | KMT2AMAPTSMN1; SMN2MEN1SLC6A3 | |
| SCHEMBL5706002 | 0.80 | KMT2A (0.63) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5179548 | 0.80 | ESR1 (1.00) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2060174 | 0.80 | CYP4F2 (0.48) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1975083 | 0.79 | HPGD (0.51) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9743098 | 0.79 | ESR1 (0.66) | ESR1ESR2KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448978-A | Novel Glucocorticoid Receptor Agonists | PFIZER LTD | 2012-05-09 | — | — | CN | claimed |
| CN-102448978-A | Novel Glucocorticoid Receptor Agonists | PFIZER LTD | 2012-05-09 | — | — | CN | disclosed |