SCHEMBL9743997

SCHEMBL9743997

CC(C)c1nc(N(C)C)c(CO)c(-c2ccc(F)cc2)c1CO

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9744135 0.90 GCGR (0.78) GCGR
SCHEMBL9743393 0.90 GCGR (0.78) GCGR
SCHEMBL8949822 0.87 GCGR (0.88) GCGR
SCHEMBL9743369 0.84 GCGR (0.56) GCGR
SCHEMBL2649256 0.84 GCGR (0.73) GCGR
SCHEMBL2647903 0.82 GCGR (1.00) GCGR
SCHEMBL8949777 0.82 GCGR (0.74) GCGR
SCHEMBL2663585 0.81 GCGR (0.77) GCGR
SCHEMBL2648281 0.80 GCGR (0.76) GCGR
SCHEMBL2647635 0.80 GCGR (1.00) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5145857-A HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 US disclosed
EP-0416383-A2 Substituted aminopyridines BAYER AG (DE) 1991-03-13 EP disclosed