SCHEMBL9744156

SCHEMBL9744156

COC(=O)C(C)C(O)C=CNC=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.32
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8023997 0.76 SMN1; SMN2 (0.37) SMN1; SMN2CA14
SCHEMBL8023996 0.76 SMN1; SMN2 (0.37) SMN1; SMN2CA14
SCHEMBL8017333 0.70 SMN1; SMN2 (0.38) SMN1; SMN2CA14
SCHEMBL784551 0.67 SMN1; SMN2 (0.52) SMN1; SMN2CA14
SCHEMBL13946795 0.67 SMN1; SMN2 (0.52) SMN1; SMN2CA14
SCHEMBL13176813 0.65 SMN1; SMN2 (0.34) SMN1; SMN2CA14
SCHEMBL8871226 0.65
SCHEMBL7123594 0.65
SCHEMBL8498697 0.65
SCHEMBL8500718 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175344-A Anticonvulsants, anxiolytic agents CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
US-5051413-A For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions CIBA-GEIGY CORPORATION (US) 1991-09-24 US disclosed