Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023996 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12MEN1TSHR | |
| SCHEMBL26463536 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2CA14 | |
| SCHEMBL4632124 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL4632127 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL8019616 | 0.78 | HDAC3 (0.35) | CA14CA12 | |
| SCHEMBL8019614 | 0.78 | HDAC3 (0.35) | CA14CA12 | |
| SCHEMBL9744156 | 0.76 | SMN1; SMN2 (0.32) | SMN1; SMN2CA14 | |
| SCHEMBL8017333 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2CA14CA12MEN1TSHR | |
| SCHEMBL6919784 | 0.75 | TP53 (0.41) | TSHR | |
| SCHEMBL10709374 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774452-B1 | Optically active compounds having plural chiral centers and the production thereof | CHISSO CORP (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0428392-B1 | Processes for the preparation of optically active compounds having plural chiral centers | CHISSO CORP (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0774452-A1 | Optically active compounds having plural chiral centers and the production thereof | Chisso Corporation (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5574182-A | HYDROLYSING 3-HYDROXYCARBOXYLIC ACID, CYCLIZING ESTER TO FORM 1,3-DIOXAN-4-ONE, DECYCLIZATION AND ESTERIFICATION | CHISSO CORPORATION (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5411877-A | Esterification | CHISSO CORPORATION (JP) | 1995-05-02 | — | — | US | disclosed |
| US-5348870-A | Using hydrolase to effect ester interchange and resolution, then alcoholysis or hydrolysis and dehydration with cyclization and crystallization | CHISSO CORPORATION (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0428392-A2 | Optically active compounds having plural chiral centers and the production thereof | Chisso Corporation (JP) | 1991-05-22 | — | — | EP | disclosed |