Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743571 | 0.86 | CYP2D6 (0.42) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9743517 | 0.86 | CYP2D6 (0.42) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9744122 | 0.86 | SMN1; SMN2 (0.39) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11864470 | 0.75 | NPSR1 (0.41) | CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL11864461 | 0.75 | NPSR1 (0.41) | CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL9744110 | 0.75 | CYP2D6 (0.41) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10583162 | 0.73 | GRIN2D (0.36) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9743641 | 0.72 | CYP2D6 (0.43) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9744920 | 0.72 | CYP2D6 (0.43) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9744240 | 0.71 | CYP2D6 (0.60) | CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175344-A | Anticonvulsants, anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |