SCHEMBL10583162

SCHEMBL10583162

CC(=C[C@@H](NC=O)C(=O)O)CP(=O)(OC(C)C)OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743571 0.85 CYP2D6 (0.42) CYP2D6CYP2C9CYP2C19
SCHEMBL9743517 0.85 CYP2D6 (0.42) CYP2D6CYP2C9CYP2C19
SCHEMBL9744044 0.81 ALDH1A1 (0.40)
SCHEMBL10582571 0.80 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8988992 0.77
SCHEMBL9744199 0.73 CYP2D6 (0.43) CYP2D6CYP2C9CYP2C19
SCHEMBL9742610 0.71 CYP2D6 (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9743641 0.70 CYP2D6 (0.43) CYP2D6CYP2C9CYP2C19
SCHEMBL9744920 0.70 CYP2D6 (0.43) CYP2D6CYP2C9CYP2C19
SCHEMBL10580256 0.69 ALOX15 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0302826-A2 Process for the preparation of unsaturated amino acid compounds CIBA-GEIGY AG (CH) 1989-02-08 EP disclosed