Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844563 | 0.87 | ESR1 (0.72) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL23212126 | 0.80 | ESR1 (0.84) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL6463791 | 0.79 | KMT2A (0.53) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL1918507 | 0.79 | KMT2A (0.71) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL30257610 | 0.78 | SERPINE1 (0.68) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL725404 | 0.78 | KMT2A (0.76) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL10854654 | 0.77 | MAPT (0.50) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL10722642 | 0.77 | KMT2A (0.55) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL8977742 | 0.77 | SELL (0.52) | MAPTKMT2AALOX15HSD17B10GAA | |
| SCHEMBL28822923 | 0.77 | KMT2A (0.69) | MAPTKMT2ASMN1; SMN2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |