Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292938 | 0.86 | ESR1 (0.66) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL2679682 | 0.82 | KMT2A (0.63) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL1786230 | 0.81 | KMT2A (0.51) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL6406532 | 0.81 | MAPT (0.44) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL16236624 | 0.80 | KMT2A (0.47) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL8766843 | 0.79 | ESR1 (0.51) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL9744231 | 0.79 | MAPT (0.56) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL777822 | 0.78 | CA1 (0.55) | KMT2AMAPTESR1ESR2MEN1 | |
| SCHEMBL1816359 | 0.78 | ALDH1A1 (0.50) | KMT2AMAPTMEN1SMN1; SMN2GAA | |
| Benzoic Acid SCHEMBL7184961 | 0.78 | HTT (0.53) | MAPTSMN1; SMN2ALOX15NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124687-A1 | Process for synthesizing d-tocotrienols | COULADOUROS ELIAS A (GR) | 2005-06-09 | — | — | US | disclosed |
| WO-2005035490-A2 | PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS | YASOO HEALTH, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| US-5393776-A | Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0571928-A1 | Acyclic Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia | Bristol-Myers Squibb Company (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0476493-A1 | Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia | Bristol-Myers Squibb Company (US) | 1992-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124687-A1 | Process for synthesizing d-tocotrienols | UGT8, DDOST, GGPS1 | KMT2A 1679/4885MAPT 4791/4885ESR1 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.