Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742469 | 0.96 | TSHR (0.50) | FFAR1TSHRHSD17B10CYP17A1MCHR1 | |
| SCHEMBL9742134 | 0.96 | FFAR1 (0.48) | FFAR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9743224 | 0.95 | TSHR (0.52) | FFAR1TSHRHSD17B10CYP17A1MCHR1 | |
| SCHEMBL9741999 | 0.95 | TSHR (0.52) | FFAR1TSHRHSD17B10CYP17A1MCHR1 | |
| SCHEMBL9742386 | 0.95 | TSHR (0.52) | FFAR1TSHRHSD17B10CYP17A1MCHR1 | |
| SCHEMBL9744090 | 0.92 | FFAR1 (0.47) | FFAR1CYP17A1MCHR1MAOBLMNA | |
| SCHEMBL9743698 | 0.92 | FFAR1 (0.47) | FFAR1TSHRHSD17B10CASP3SENP8 | |
| SCHEMBL9742589 | 0.90 | FFAR1 (0.46) | FFAR1TSHRHSD17B10CASP3SENP8 | |
| SCHEMBL9743234 | 0.90 | FFAR1 (0.46) | FFAR1TSHRHSD17B10CASP3SENP8 | |
| SCHEMBL9744328 | 0.90 | FFAR1 (0.46) | FFAR1TSHRHSD17B10CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |