Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743427 | 1.00 | S1PR3 (0.41) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9744280 | 1.00 | S1PR3 (0.41) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9743422 | 1.00 | S1PR3 (0.41) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9743678 | 0.99 | RAB9A (0.41) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9743688 | 0.99 | RAB9A (0.41) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9742385 | 0.92 | S1PR3 (0.40) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9742975 | 0.92 | S1PR3 (0.40) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9744050 | 0.92 | S1PR3 (0.40) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9742628 | 0.92 | S1PR3 (0.40) | S1PR3RAB9ALMNAHRH3CYP2C9 | |
| SCHEMBL9743066 | 0.92 | S1PR3 (0.40) | S1PR3RAB9ALMNAHRH3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |