Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL9744629

CC(C)(C)c1ccccc1O.S

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.95
TDP1 Q9NUW8 2/20 0.95
TSHR P16473 2/20 0.95
CA2 P00918 5/20 0.56
ALOX15 P16050 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TYR P14679 2/20 0.50
NR1I2 O75469 1/20 0.50
CYP2C9 P11712 1/20 0.50
MIF P14174 1/20 0.50
HTT P42858 1/20 0.50
NFE2L2 Q16236 1/20 0.50
GABRA1 P14867 2/20 0.48
GABRB2 P47870 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 3/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
ATP2A2 P16615 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL15667759 1.00 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Hydrogen Sulfide SCHEMBL4882848 1.00 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Hydrogen Sulfide SCHEMBL11637129 1.00 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL51803 0.97 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL29358279 0.97 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL22729938 0.97 ALDH1A1 (1.00) ALDH1A1TDP1TSHRCA2ALOX15
SCHEMBL23542116 0.95 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Ethyne SCHEMBL3701741 0.95 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Ethane SCHEMBL8319752 0.95 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15
Bromide SCHEMBL6853237 0.95 ALDH1A1 (0.95) ALDH1A1TDP1TSHRCA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113491684-A Application of dithiodipyrone and analogue thereof in preventing and treating organ injury diseases caused by coronavirus pneumonia (containing COVID-19) 北京中美红格科技有限公司 2021-10-12 CN claimed
CN-113491683-A Application of dithiodipyrone and analogue in preparation of medicine for preventing and treating coronavirus pneumonia (including COVID-19) 北京中美红格科技有限公司 2021-10-12 CN claimed
CN-113209061-A Pharmaceutical composition and preparation containing disulfotol and analogue for preventing and treating coronavirus pneumonia (containing COVID-19) 北京中美红格科技有限公司 2021-08-06 CN claimed
CN-113171360-A Application of dithiodipyrone and analog thereof in preparation of medicine for preventing and treating heart tissue damage diseases caused by antitumor doxorubicin chemotherapy 北京中美红格科技有限公司 2021-07-27 CN claimed
EP-0220660-B1 SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
US-4704324-A REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION THE DOW CHEMICAL COMPANY (US) 1987-11-03 US claimed
WO-1987002682-A1 SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1987-05-07 WO claimed
EP-0220660-A2 Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups THE DOW CHEMICAL COMPANY (US) 1987-05-06 EP claimed
CN-113491684-A Application of dithiodipyrone and analogue thereof in preventing and treating organ injury diseases caused by coronavirus pneumonia (containing COVID-19) 北京中美红格科技有限公司 2021-10-12 CN disclosed
CN-113491683-A Application of dithiodipyrone and analogue in preparation of medicine for preventing and treating coronavirus pneumonia (including COVID-19) 北京中美红格科技有限公司 2021-10-12 CN disclosed
CN-113209061-A Pharmaceutical composition and preparation containing disulfotol and analogue for preventing and treating coronavirus pneumonia (containing COVID-19) 北京中美红格科技有限公司 2021-08-06 CN disclosed
CN-113171360-A Application of dithiodipyrone and analog thereof in preparation of medicine for preventing and treating heart tissue damage diseases caused by antitumor doxorubicin chemotherapy 北京中美红格科技有限公司 2021-07-27 CN disclosed
EP-2776889-A1 ACTINIC RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM Corporation (JP) 2014-09-17 EP disclosed
WO-2013069753-A1 ACTINIC RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2013-05-16 WO disclosed
EP-0220660-B1 SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP disclosed
US-4839203-A COVALENT BONDING PRODUCING A COMPOSITE THE DOW CHEMICAL COMPANY (US) 1989-06-13 US disclosed
US-4797187-A COACERVATION OF CATIONS THE DOW CHEMICAL COMPANY (US) 1989-01-10 US disclosed
US-4704324-A REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION THE DOW CHEMICAL COMPANY (US) 1987-11-03 US disclosed
WO-1987002682-A1 SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1987-05-07 WO disclosed
EP-0220660-A2 Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups THE DOW CHEMICAL COMPANY (US) 1987-05-06 EP disclosed