Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512566 | 1.00 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9745679 | 1.00 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL7449138 | 1.00 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3505730 | 0.83 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3505731 | 0.83 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9786445 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9786423 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9786424 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9786427 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9786443 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |