Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439285 | 0.84 | ALOX5 (0.60) | L3MBTL1CYP1A2CYP2D6ALOX5CYP3A4 | |
| SCHEMBL8128564 | 0.84 | ALOX5 (0.57) | MAPTL3MBTL1CYP1A2CYP2D6ALOX5 | |
| SCHEMBL8133629 | 0.80 | MAPT (0.55) | MAPTHTTTDP1L3MBTL1CYP1A2 | |
| SCHEMBL9217493 | 0.77 | CYP1A2 (0.44) | MAPTL3MBTL1CYP1A2CYP2D6ALOX5 | |
| SCHEMBL9439503 | 0.77 | ALOX5 (0.58) | L3MBTL1CYP1A2CYP2D6ALOX5CYP3A4 | |
| SCHEMBL22380032 | 0.77 | DYRK1A (0.45) | MAPTTDP1DYRK1AALDH1A1HSD17B10 | |
| SCHEMBL9743956 | 0.76 | ALOX5 (0.48) | MAPTHTTL3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL9439898 | 0.75 | MAPT (0.63) | MAPTHTTTDP1L3MBTL1CYP1A2 | |
| SCHEMBL9185540 | 0.74 | ALOX5 (0.44) | L3MBTL1CYP1A2CYP2D6ALOX5CYP3A4 | |
| SCHEMBL1512366 | 0.74 | SMN1; SMN2 (0.65) | CYP1A2CYP3A4CYP2C19DYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |