Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908273 | 0.82 | HDAC3 (0.41) | HDAC3HDAC1HDAC2NCOR2NPSR1 | |
| SCHEMBL9744817 | 0.79 | HDAC3 (0.38) | HDAC3HDAC1HDAC2NCOR2NPSR1 | |
| SCHEMBL23074190 | 0.76 | CA2 (0.50) | PPARGPPARASLC7A5MEN1KMT2A | |
| SCHEMBL17544325 | 0.75 | HDAC3 (0.39) | HDAC3HDAC1HDAC2NCOR2NPSR1 | |
| SCHEMBL381382 | 0.71 | GSR (0.38) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL9744822 | 0.71 | SYK (0.44) | HDAC1PPARGPPARACA12CA1 | |
| SCHEMBL1726210 | 0.68 | MAPT (0.43) | PPARGPPARACA1CA2CA9 | |
| SCHEMBL1726216 | 0.68 | MAPT (0.43) | PPARGPPARACA1CA2CA9 | |
| SCHEMBL22158837 | 0.68 | KMT2A (0.53) | L3MBTL1ALDH1A1HPGDKMT2ACA2 | |
| SCHEMBL27786436 | 0.68 | KMT2A (0.54) | ALDH1A1KMT2ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098996-A | Fluorination of compounds for use in diagnosis of nuclear medicine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-03-24 | — | — | US | disclosed |