Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095121 | 0.78 | POLB (0.37) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL188469 | 0.78 | SMN1; SMN2 (0.44) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL1419365 | 0.78 | CYP2A6 (0.48) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL17843111 | 0.78 | KDM4E (0.39) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL14784924 | 0.77 | MEN1 (0.48) | POLBNOS1KDM4ENOS3HCRTR1 | |
| SCHEMBL5848405 | 0.77 | L3MBTL1 (0.50) | POLBHCRTR1HCRTR2 | |
| SCHEMBL1419853 | 0.77 | HRH1 (0.49) | — | |
| SCHEMBL16213011 | 0.77 | KDM4E (0.38) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL16213390 | 0.75 | KDM4E (0.41) | POLBKDM4EHCRTR1HCRTR2 | |
| SCHEMBL10483845 | 0.75 | MC4R (0.44) | NOS1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205068-B1 | LYSERGIC-ACID AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-01-02 | — | — | EP | claimed |