Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.58 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25471797 | 0.96 | TYR (0.54) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL3642865 | 0.93 | ALDH1A1 (0.55) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL3642862 | 0.93 | ALDH1A1 (0.55) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL9744259 | 0.91 | TYR (0.58) | TYRMBTPS1CTSLCTSBCTSS | |
| SCHEMBL29559972 | 0.88 | TYR (0.62) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL5802843 | 0.88 | TYR (0.62) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL7437357 | 0.88 | TYR (0.62) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL29774427 | 0.87 | TYR (0.54) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL25471796 | 0.87 | TYR (0.54) | TYRCTSLCTSBCTSSTACR1 | |
| SCHEMBL25471896 | 0.86 | TYR (0.52) | TYRCTSLCTSBCTSSTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309827-B1 | L-DOPA DERIVATIVES OR THEIR ACID ADDITION SALTS, PROCESS FOR PRODUCING SAME AND THEIR USE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-4966915-A | L-dopa derivatives or their acid addition salts, process for producing same and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0309827-A1 | L-Dopa derivatives or their acid addition salts, process for producing same and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |