Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31493862 | 0.79 | KDM4E (0.41) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL23600930 | 0.79 | CA1 (0.40) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL3371190 | 0.78 | TPMT (0.52) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL23600929 | 0.76 | SELL (0.54) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL23600935 | 0.76 | CSNK2A1 (0.44) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL17893926 | 0.76 | CA1 (0.38) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL4382058 | 0.74 | KDM4E (0.43) | ALDH1A1PTGS2THRBKDM4EHPGD | |
| SCHEMBL23756593 | 0.74 | CSNK2A1 (0.42) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL163610 | 0.73 | CA1 (0.59) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL419764 | 0.73 | CA1 (0.52) | CA1CA2ALDH1A1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094943-A | Superoxide dimutase | BOEHRINGER MANNHEIM GMBH (DE) | 1992-03-10 | — | — | US | disclosed |