Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.84 |
| ▸ | PTGFR | P43088 | 5/20 | 0.84 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.84 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.60 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744939 | 1.00 | TBXA2R (0.84) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626383 | 1.00 | TBXA2R (0.84) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626386 | 1.00 | TBXA2R (0.84) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL11484121 | 0.91 | PTGFR (1.00) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL3366405 | 0.91 | PTGFR (1.00) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626361 | 0.90 | PTGFR (0.68) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626364 | 0.90 | PTGFR (0.68) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10627456 | 0.90 | PTGFR (0.68) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10424949 | 0.90 | PTGFR (0.68) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL9721770 | 0.89 | TBXA2R (0.84) | TBXA2RPTGFRPTGER3PTGER1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243369-B1 | 9-HALOGEN PROSTAGLANDINE CLATHRATES AND UTILIZATION THEREOF AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | claimed |
| US-4789685-A | 9-fluoroprostaglandin derivatives, their preparation and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | claimed |
| US-4626531-A | Prostaglandins and antigestagens for induction of labor and for abortion | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | claimed |
| EP-0243369-B1 | 9-HALOGEN PROSTAGLANDINE CLATHRATES AND UTILIZATION THEREOF AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5047525-A | With cyclodextrin ty | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0179421-B1 | ANTIGESTAGENS, GLUCOCORTICOIDS AND PROSTAGLANDINS FOR INDUCTION OF LABOUR OR INTERRUPTION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |
| US-4789685-A | 9-fluoroprostaglandin derivatives, their preparation and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | disclosed |
| US-4626531-A | Prostaglandins and antigestagens for induction of labor and for abortion | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | disclosed |
| EP-0069696-B1 | DERIVATIVES OF 9-FLUOROPROSTAGLANDIN, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0139608-A2 | Prostaglandins and antigestagens for the onset of labour or for the interruption of pregnancy | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-02 | — | — | EP | disclosed |
| US-4454339-A | 9-Fluoroprostaglandin derivatives, and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-06-12 | — | — | US | disclosed |
| EP-0069696-A2 | Derivatives of 9-fluoroprostaglandin, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-01-12 | — | — | EP | disclosed |