Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 13/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 6/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 4/20 | 1.00 |
| ▸ | PTGER1 | P34995 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.71 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.71 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484121 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL10626386 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL10882717 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| Nocloprost SCHEMBL1554648 | 0.91 | PTGER3 (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL10882711 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL9744927 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL9721770 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| Nocloprost SCHEMBL436204 | 0.91 | PTGER3 (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| Nocloprost SCHEMBL1554645 | 0.91 | PTGER3 (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL9721774 | 0.91 | TBXA2R (0.84) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349242-B1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS INC (US) | 2018-12-05 | — | — | EP | disclosed |
| US-8722739-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20140031423-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-8623918-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8470882-B2 | — | — | 2013-06-25 | — | — | US | disclosed |
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-4256745-A | OXYTOCICS; DURABILITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4159343-A | ABORTIFICANTS, LABOR INDUCTION, MENSTRUAL CYCLE REGULATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-4105792-A | OXYTOCICS, ABORTION INDUCTION | SCHERING AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | PTGFR 7/4885PTGER3 16/4885TBXA2R 22/4885 |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | PTGFR 7/4885PTGER3 16/4885TBXA2R 22/4885 |
| US-20140031423-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | PTGFR 7/4885PTGER3 16/4885TBXA2R 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.