Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095186 | 0.89 | GCGR (0.56) | GCGRDHODHLMNASMN1; SMN2NPC1 | |
| SCHEMBL9870958 | 0.88 | GCGR (0.72) | GCGRDHODHLMNAFABP3FABP4 | |
| SCHEMBL5094915 | 0.87 | GCGR (0.59) | GCGRDHODHLMNASMN1; SMN2NPC1 | |
| SCHEMBL6565362 | 0.85 | GCGR (0.79) | GCGRDHODHLMNASMN1; SMN2NPC1 | |
| SCHEMBL8949663 | 0.82 | GCGR (0.61) | GCGRDHODHLMNAFABP3FABP4 | |
| SCHEMBL5102048 | 0.82 | GCGR (0.70) | GCGRDHODHLMNASMN1; SMN2NPC1 | |
| SCHEMBL5101592 | 0.81 | GCGR (0.57) | GCGRDHODHLMNAFABP3FABP4 | |
| SCHEMBL9744532 | 0.81 | GCGR (0.63) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL5095179 | 0.79 | GCGR (0.57) | GCGRDHODHLMNASMN1; SMN2NPC1 | |
| SCHEMBL2651071 | 0.79 | GCGR (0.56) | GCGRFABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145857-A | HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |