Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198342 | 0.85 | KMT2A (0.70) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL11375431 | 0.81 | MAPK1 (0.71) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL9442138 | 0.81 | MAPK1 (0.74) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| Carboxin SCHEMBL18392 | 0.75 | MAPK1 (1.00) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL14439499 | 0.74 | HSD17B10 (0.68) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL9198177 | 0.74 | RAB9A (0.56) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL3971421 | 0.73 | MAPK1 (0.67) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL11163951 | 0.72 | MAPK1 (0.64) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL9206415 | 0.71 | MAPK1 (0.60) | RAB9AKMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL9206336 | 0.71 | MAPK1 (0.64) | RAB9AKMT2AMEN1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |