Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 2/20 | 0.49 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501822 | 0.87 | TDP1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9730522 | 0.87 | TDP1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9501830 | 0.87 | TDP1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT | |
| Hydrogen Sulfide SCHEMBL28800554 | 0.83 | TDP1 (0.58) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL7106613 | 0.81 | TDP1 (0.63) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9744956 | 0.78 | TDP1 (0.59) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL5884248 | 0.78 | TDP1 (0.59) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9168674 | 0.78 | TDP1 (0.59) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL2140382 | 0.77 | TDP1 (0.63) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL29958345 | 0.77 | TDP1 (0.63) | TDP1CYP11B1CYP11B2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214600-B1 | CEPHALOSPORIN DERIVATIVES | Otsuka Kagaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4906623-A | 3-Imidazolium cephalosporin derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0214600-A2 | Cephalosporin derivatives | Otsuka Kagaku Kabushiki Kaisha (JP) | 1987-03-18 | — | — | EP | disclosed |