Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28800554

FC(F)=CCn1cnc2ccccc21.S

nearest known ligand 0.58

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.58
CYP11B1 P15538 5/20 0.51
CYP11B2 P19099 5/20 0.51
TNF P01375 1/20 0.51
EGLN3 Q9H6Z9 1/20 0.50
HTT P42858 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
LMNA P02545 2/20 0.49
FDPS P14324 2/20 0.48
GGPS1 O95749 1/20 0.48
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
MAPK1 P28482 1/20 0.47
APAF1 O14727 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745498 0.83 TDP1 (0.58) TDP1CYP11B1CYP11B2TNFEGLN3
Hydrogen Sulfide SCHEMBL29074168 0.80 TDP1 (0.58) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL5884248 0.78 TDP1 (0.59) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL326813 0.77 TDP1 (0.63) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL2140382 0.77 TDP1 (0.63) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL7106613 0.77 TDP1 (0.63) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL29958345 0.77 TDP1 (0.63) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL7160203 0.76 TDP1 (0.61) TDP1CYP11B1CYP11B2TNFEGLN3
Bromide SCHEMBL11005339 0.76 TDP1 (0.61) TDP1CYP11B1CYP11B2TNFEGLN3
SCHEMBL9501830 0.75 TDP1 (0.47) TDP1CYP11B1CYP11B2TNFEGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685495-A N-difluoromethyl dinitrogen heterocyclic selenourea compounds with insecticidal, antibacterial, herbicidal and anticancer effects, and preparation and application thereof 华南农业大学 2022-07-01 CN disclosed