Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379049 | 1.00 | ALDH1A1 (0.52) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL19975703 | 0.98 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL17914173 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL7939776 | 0.84 | EPHX2 (0.62) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL28177818 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058928 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058893 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058434 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL2058987 | 0.84 | ALDH1A1 (0.54) | ALDH1A1EPHX2CES2CES1GPR84 | |
| SCHEMBL3627173 | 0.84 | EPHX2 (0.62) | ALDH1A1EPHX2CES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099056-A | PROCESS FOR THE PRODUCTION OF N-SUBSTITUTED-AMINOMETHYLPHOSPHONIC ACID DIALKYLESTERS AND OF THE CORRESPONDING ACIDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-03-24 | — | — | US | disclosed |
| US-4830788-A | Process for preparation of substituted-aminomethylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4351779-A | Process for the production of methylaminomethylphosphonic acid esters | CIBA-GEIGY CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4160779-A | Process for the production of methylaminomethylphosphonic acid and its salts | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |