SCHEMBL9745541

SCHEMBL9745541

C=C(CC(Cl)Cl)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TGFBR1 P36897 1/20 0.31
TET2 Q6N021 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24800768 0.83 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL27392611 0.81 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL4887464 0.79 ALDH1A1 (0.44) ALDH1A1TGFBR1TET2EGLN1TSHR
SCHEMBL28703822 0.79 ALDH1A1 (0.44) ALDH1A1TGFBR1TET2EGLN1TSHR
SCHEMBL9747118 0.78 ALDH1A1 (0.44) ALDH1A1EGLN1TSHR
SCHEMBL9746817 0.78 TSHR (0.36) TSHR
SCHEMBL6891698 0.77 ALDH1A1 (0.42) ALDH1A1TGFBR1TET2EGLN1TSHR
SCHEMBL9746204 0.77 ALDH1A1 (0.42) ALDH1A1TGFBR1TET2EGLN1TSHR
SCHEMBL9747111 0.77 ALDH1A1 (0.42) ALDH1A1TGFBR1TET2EGLN1TSHR
SCHEMBL27435025 0.77 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed