Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GMNN | O75496 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743285 | 1.00 | MAPK1 (0.62) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9743416 | 1.00 | MAPK1 (0.62) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9742627 | 0.98 | MAPK1 (0.59) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9744369 | 0.93 | MAPK1 (0.51) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL16272808 | 0.89 | MAPK1 (0.60) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9743044 | 0.86 | MAPK1 (0.42) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29086123 | 0.86 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL4625835 | 0.86 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL28366828 | 0.86 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL28591802 | 0.86 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128252-A | Resolution of optically active esters, transesterification, lipase | CHISSO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |