Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746510 | 0.93 | TP53 (0.36) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL9746121 | 0.88 | PCSK9 (0.37) | CES2CES1PCSK9LMNAPTGS2 | |
| SCHEMBL9745630 | 0.86 | TP53 (0.38) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL9747079 | 0.77 | TP53 (0.35) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL9748063 | 0.76 | TP53 (0.33) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL25359877 | 0.72 | TP53 (0.38) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL9746784 | 0.72 | TP53 (0.38) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL10932716 | 0.72 | TP53 (0.38) | TP53HPGDCES2CES1PCSK9 | |
| SCHEMBL9745998 | 0.71 | HPGD (0.33) | TP53HPGD | |
| SCHEMBL9746969 | 0.70 | TP53 (0.36) | TP53HPGDCES2CES1PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |