Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745597 | 0.86 | TP53 (0.32) | TP53LMNAATMTRPA1CES2 | |
| SCHEMBL9746121 | 0.83 | PCSK9 (0.37) | LMNACES2CES1PCSK9 | |
| SCHEMBL9746510 | 0.82 | TP53 (0.36) | TP53LMNAATMTRPA1CES2 | |
| SCHEMBL9746784 | 0.79 | TP53 (0.38) | TP53LMNAATMCES2CES1 | |
| SCHEMBL9746969 | 0.77 | TP53 (0.36) | TP53LMNAATMCES2CES1 | |
| SCHEMBL11254087 | 0.75 | TP53 (0.35) | TP53LMNAATMCES2CES1 | |
| SCHEMBL25355509 | 0.72 | TP53 (0.48) | TP53LMNAATMCES2CES1 | |
| SCHEMBL1031778 | 0.72 | TP53 (0.41) | TP53LMNAATMCES2CES1 | |
| SCHEMBL898908 | 0.72 | TP53 (0.48) | TP53LMNAATMCES2CES1 | |
| SCHEMBL1029950 | 0.72 | TP53 (0.41) | TP53LMNAATMCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |