Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 4/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304397 | 1.00 | HPGD (0.53) | HPGDPLK1THRATHRBPOLB | |
| SCHEMBL5316777 | 1.00 | HPGD (0.53) | HPGDPLK1THRATHRBPOLB | |
| SCHEMBL9491957 | 1.00 | HPGD (0.53) | HPGDPLK1THRATHRBPOLB | |
| SCHEMBL5683064 | 0.98 | HPGD (0.54) | HPGDPLK1THRATHRBPOLB | |
| SCHEMBL10528635 | 0.94 | SLC2A1 (0.51) | HPGDPLK1THRATHRBPOLB | |
| SCHEMBL424971 | 0.91 | HPGD (0.56) | HPGDPOLBMAOAMAOBNPC1 | |
| SCHEMBL5169781 | 0.91 | POLB (0.54) | HPGDPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11569857 | 0.91 | THRB (0.56) | PLK1THRATHRBMAOAMAOB | |
| SCHEMBL11567371 | 0.91 | THRB (0.56) | PLK1THRATHRBMAOAMAOB | |
| SCHEMBL21575599 | 0.91 | THRB (0.56) | PLK1THRATHRBMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313474-B1 | AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |