Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746177 | 0.79 | TDP1 (0.33) | TDP1KDM4EALDH1A1TSHRTAAR1 | |
| SCHEMBL29819752 | 0.79 | TDP1 (0.33) | TDP1KDM4EALDH1A1TSHRTAAR1 | |
| SCHEMBL9746483 | 0.77 | TDP1 (0.32) | TDP1KDM4EALDH1A1TSHRTAAR1 | |
| SCHEMBL1452401 | 0.72 | TDP1 (0.36) | TDP1KDM4EALDH1A1TSHRTAAR1 | |
| SCHEMBL25291459 | 0.72 | TDP1 (0.36) | TDP1KDM4EALDH1A1TSHRTAAR1 | |
| SCHEMBL9746053 | 0.72 | TP53 (0.32) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL9746333 | 0.72 | RIPK1 (0.31) | — | |
| SCHEMBL6908951 | 0.69 | TSHR (0.37) | ALDH1A1TSHRCYP2A6LMNAALOX12 | |
| SCHEMBL8147062 | 0.69 | TSHR (0.37) | ALDH1A1TSHRCYP2A6LMNAALOX12 | |
| SCHEMBL9746401 | 0.69 | TSHR (0.37) | ALDH1A1TSHRCYP2A6LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |