SCHEMBL9745674

SCHEMBL9745674

CCCCC[Si](O)(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
EPHX1 P07099 4/20 0.33
CES2 O00748 4/20 0.33
CES1 P23141 4/20 0.33
AKR1B1 P15121 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3481973 0.91 TSHR (0.35) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL28014427 0.88 TSHR (0.33) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL618894 0.88 TSHR (0.44) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL2922266 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL17090784 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL2920815 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL10984369 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL2917797 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL618296 0.85 TSHR (0.50) TSHRTHRBSMN1; SMN2LMNAALDH1A1
SCHEMBL3482477 0.85 TSHR (0.35) TSHRTHRBSMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed