SCHEMBL9745795

SCHEMBL9745795

C=CCc1cc2c(c(OC)c1)OOC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
CYP3A4 P08684 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
POLB P06746 2/20 0.44
ALOX15 P16050 2/20 0.44
PTGS1 P23219 2/20 0.44
ALOX5 P09917 2/20 0.44
AR P10275 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
TNKS O95271 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678691 0.77 CYP3A4 (0.56) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
SCHEMBL3690822 0.72 CYP3A4 (0.61) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
SCHEMBL286747 0.72 CYP3A4 (0.51) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
Elemicin SCHEMBL68041 0.72 CYP3A4 (1.00) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
Elemicin SCHEMBL30363316 0.72 CYP3A4 (1.00) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
Elemicin SCHEMBL10728512 0.72 CYP3A4 (1.00) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
Elemicin SCHEMBL28330527 0.71 CYP3A4 (0.97) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
Elemicin SCHEMBL28810327 0.71 CYP3A4 (0.97) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
SCHEMBL68542 0.70 ALDH1A1 (0.63) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD
SCHEMBL15004119 0.70 ALDH1A1 (0.63) ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5174804-A Briquets VIGORO INDUSTRIES, INC. (US) 1992-12-29 US disclosed