Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746114 | 0.91 | ALDH1A1 (0.56) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL9746795 | 0.90 | AR (0.53) | ARALDH1A1CYP19A1SLC6A4MAOB | |
| SCHEMBL9746077 | 0.88 | ALDH1A1 (0.57) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL9745799 | 0.88 | ALDH1A1 (0.57) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL9747910 | 0.88 | ALDH1A1 (0.57) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL4103326 | 0.86 | HTR2A (0.53) | ARSCN9AHPGDALDH1A1HTR2A | |
| SCHEMBL1940627 | 0.86 | AR (0.57) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL9746883 | 0.84 | AR (0.53) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL28487747 | 0.82 | ALDH1A1 (0.57) | ARHPGDALDH1A1CYP19A1MAOB | |
| SCHEMBL9745869 | 0.82 | ALDH1A1 (0.52) | ARHPGDALDH1A1CYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |