SCHEMBL9745919

SCHEMBL9745919

CC(=O)Nc1ccc2cccc3c4cccc5cccc(c1c23)c54

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.71
KDM4E B2RXH2 4/20 0.71
HPGD P15428 4/20 0.71
MAPT P10636 1/20 0.71
RXFP1 Q9HBX9 1/20 0.46
CYP1A2 P05177 2/20 0.44
HSD17B10 Q99714 2/20 0.44
THRB P10828 1/20 0.44
GAA P10253 2/20 0.43
GLA P06280 1/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.42
CASP6 P55212 1/20 0.42
LMNA P02545 1/20 0.42
MAOA P21397 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA12 O43570 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9229468 0.83 KDM4E (0.59) ALDH1A1KDM4EHPGDMAPTCYP1A2
SCHEMBL29581351 0.83 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL5054452 0.83 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL8332038 0.81 KDM4E (0.63) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL8333926 0.81 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL8333925 0.81 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL3781796 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL6542121 0.76 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDMAPTCYP1A2
SCHEMBL20436327 0.74 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDMAPTRXFP1
SCHEMBL3513570 0.74 MAPT (0.57) ALDH1A1KDM4EHPGDMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US claimed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed