SCHEMBL9745960

SCHEMBL9745960

N#Cc1ccc(Oc2ccc(Oc3ccc(C(F)(F)F)cc3)cc2)cc1C#N

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.56
CYP19A1 P11511 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522240 1.00 AR (0.56) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL9746494 0.94 AR (0.55) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL9745707 0.87 AR (0.55) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL1373374 0.87 AR (0.50) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL30478014 0.87 AR (0.50) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL24749621 0.85 AR (0.52) AR
SCHEMBL30360761 0.85 AR (0.56) ARCYP19A1ALDH1A1HPGD
SCHEMBL29938879 0.85 AR (0.49) AR
SCHEMBL20511050 0.85 AR (0.56) ARCYP19A1ALDH1A1HPGD
SCHEMBL30768289 0.85 AR (0.52) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118431-A Phthalonitriles and phthalocyanines as lubricity-enhancing additives THE DOW CHEMICAL COMPANY (US) 1992-06-02 US disclosed
US-5061388-A Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives THE DOW CHEMICAL COMPANY (US) 1991-10-29 US disclosed