SCHEMBL30478014

SCHEMBL30478014

N#Cc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(C#N)c(C#N)c4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1C#N

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.50
CYP19A1 P11511 1/20 0.48
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
NPSR1 Q6W5P4 1/20 0.43
PDE4B Q07343 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1373374 1.00 AR (0.50) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL19280731 0.93 ESR1 (0.50) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL522240 0.87 AR (0.56) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL9745960 0.87 AR (0.56) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL12215129 0.83 AR (0.38) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL20230322 0.83 L3MBTL1 (0.48) ARCYP19A1NPSR1
SCHEMBL1377229 0.82 CYP19A1 (0.62) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL9472016 0.82 CYP19A1 (0.62) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL8426309 0.82 AR (0.46) ARCYP19A1ALDH1A1HPGDNPSR1
SCHEMBL9746494 0.81 AR (0.55) ARCYP19A1ALDH1A1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961323-B Fluorinated benzonitrile and fluorinated epoxy resin composite material and preparation method thereof 广东炜林纳新材料科技股份有限公司 2023-06-06 CN disclosed